White Papers

The white papers are designed to provide healthcare professionals with in-depth insights into the clinical applications of our bioabsorbable implants. These publications highlight how our solutions can advance patient care and support surgeons.

Please visit our Clinical Evidence page to find our evidence-based pre-clinical and clinical references, in vitro and biomechanical studies as well as literature reviews mentioning the application of Inion® products in published peer-reviewed journals. More than 300,000 surgeries have been conducted using Inion® implants since 2001.

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Inion White Papers

Antibacterial, Osteoconductive and Osteostimulative Properties of Inion BioRestore™

2025-11, ©Inion Oy
Inion BioRestore™ is a bioactive and bioabsorbable synthetic bone graft substitute designed to support safe and effective bone regeneration. Its porous structure promotes bone ingrowth and remodeling while gradually resorbing into new bone. Inion BioRestore™ combines osteoconductive and osteostimulative properties that enhance osteoblast activity and accelerate bone healing. Moreover, its antibacterial effect helps reduce the risk of postoperative infections. As a fully synthetic and biocompatible material, Inion BioRestore™ eliminates donor site morbidity and supports predictable clinical outcomes in maxillofacial, orthopaedic, and spinal applications. Full text (PDF)

Key Clinical Benefits of Inion® Bioabsorbable Implants for Healthcare Providers

2025-8, ©Inion Oy
Bioabsorbable implants have transformed fracture fixation and orthopaedic treatment by offering a viable alternative to permanent metal hardware. The application of bioabsorbable implants has broadened across various surgical fields, including trauma, sports medicine, and craniomaxillofacial surgery. These implants support healing while naturally degrading, which helps eliminate the long-term complications often associated with metal implants. Here, we present the key clinical benefits of Inion® bioabsorbable implants for healthcare providers. These include the elimination of permanent implants, reduced need for revision surgeries, preservation of standard recovery timelines, more efficient allocation of healthcare resources, and measurable cost savings for healthcare systems. Full text (PDF)

The Burden of Hardware Removal

2021-6, ©Inion Oy
Historically, metal has been the most popular material for fracture fixation. Metal implants provide strong fixation during bone healing but remain in the patient’s body permanently unless subsequently surgically removed. The reasons for hardware removal include pain and soft tissue irritation, deep late infection, metal allergy or toxicity, hardware migration, metal failure, and secondary fracture. The hardware removal rates reported by previous studies have varied between 12% and 80% (Partio et al. 2020). While the removal of hardware after fracture surgery is often a straightforward procedure, it can be more challenging and does not come without both its complications and costs to patients, institutions and society. Full text (PDF)